SARmont LLC is an organic synthesis and medicinal chemistry consulting firm located in the Saint Louis , Missouri (USA). Efforts are led by Dr. John J. Talley is considered one of the world's most accomplished medicinal chemists. He is best known as the co-inventor of the blockbuster COX-2 inhibitor celecoxib (Celebrex®) and follow-on coxibs Bextra® and Dynastat®. In addition, John played a major role in the discovery of the HIV protease inhibitors Agenerase®, Lexiva®, and Prezista®. In all, he is a co-inventor of eight marketed drugs, with several more still in development. Dr. Talley has successfully defended patents in litigation as an expert witness and is named an inventor on more than 200 issued U.S. drug patents.
Dr. Talley uses a combination of rational drug design, insightful activity trend analysis, informed interpretation of medical need, and careful synthetic planning to achieve success. SARmont specializes in challenging, multi-step synthesis of compounds for the pharmaceutical, biotechnology, and agrochemical industries.
Accolades and Awards:
PhRMA Discoverers Award in 2002 for the discovery of Celebrex®
American Chemical Society Award: Saint Louis Chapter in 2001
Medicine Maker’s 2015 Power List
• Custom synthesis for the pharmaceutical and biotechnology industries
• Authentic samples of biologically active compounds
• Analog synthesis
• Lead optimization
• Key intermediates and building blocks
• Synthesis of metabolites
• Chemical consultant
• Intellectual property
• Process research
• Expert Witness